Dr. Mark E. Cook received his Ph.D. in Poultry Nutrition/Immunology from Louisiana State University in 1982.

He then took a postdoctoral position in the laboratory of Dr. Milton Sunde at the University of Wisconsin-Madison in the Department of Poultry Science. He accepted a position as Assistant Professor at UW-Madison in 1983, became an Associate Professor in 1990 and a full Professor in 1992. He currently is on the faculty of the Department of Animal Sciences, directs the Poultry Research Institute at UW-Madison, and holds affiliate appointments in the Department of Nutritional Sciences, Department of Food and Microbiology and the Center for Environmental Toxicology.

Mark teaches Comparative Nutrition, Avian Health, Introduction to Animal Sciences, Food Toxicology, and Immunotoxicology.

He also typically advises 14 undergraduates in the Animal Sciences and Biology majors.

Mark has and does serve as a research mentor to graduate students. So far, 10 M.S. and 11Ph.D. have been completed in his lab and 1M.S. and 3Ph.D. are in progress.

His research focus is on the nutritional regulation of immune function.

Mark has spoken at 70 'invited talks' over the past 7 years.

He has authored/coauthored over 95 peer reviewed articles and has been involved in popular press releases and selected national news releases that involve his research.

  • BS, Microbiology, Louisiana State University 1978
  • MS, Poultry Nutrition, Louisiana State University 1980
  • PhD, Poultry Nutrition/ Immunology, Louisiana State University 1982
  • Post doctoral, Poultry Science Department, University of Wisconsin - Madison 1982 - 1983

Arendt MK, Sand JM, Marcone TM, Cook ME.Interleukin-10 neutralizing antibody for detection of intestinal luminal levels and as a dietary additive in Eimeria challenged broiler chicks. Poult Sci. 2016 Feb 1. pii: pev365. [Epub ahead of print]

Sand JM, Arendt MK, Repasy A, Deniz G, Cook ME. Oral antibody to interleukin-10 reduces growth rate depression due to Eimeria spp. infection in broiler chickens. Poult Sci. 2016 Jan 15. pii: pev352. [Epub ahead of print]

Bobeck EA, Hellestad EM, Sand JM, Piccione ML, Bishop JW, Helvig C, Petkovich M, Cook ME. 2015. Oral peptide specific egg antibody to intestinal sodium-dependent phosphate co-transporter-2b is effective at altering phosphate transport in vitro and in vivo. Poult Sci. 2015 94:1128-1137.

Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, Cook ME, Suresh M, Gellman SH. 2015. Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes. ACS Chem Biol. Mar 20;10(3):844-54.

Bobeck, E.A., D.K. Combs, and M.E. Cook. 2014. Introductory animal science-based instruction influences attitudes on animal agriculture issues. J. Anim. Sci. 92:856-864

Boriosi, J.P., Maki, D.G., Yngsdal-Krenz, R.A., Wald, E.R., Porter, W.P., Cook, M.E., Butz, D.E. 2014. Breath carbon isotope delta value may be a biomarker of catabolic inflammatory acute phase response in mechanically ventilated pediatric patients. J. Anal. At. Spectrom.  29:599-605.

Butz, D.E., Morello, S.L., Sand, J., Boriosi, J.P., Holland, G.N. Cook, M.E. 2014. Expired breath carbon delta value is a marker for the onset of sepsis in a swine model. J. Analytical Atomic Spec. 29:606-613

Heying EK, Tanumihardjo JP, Vasic V, Cook M, Palacios-Rojas N, Tanumihardjo SA. Biofortified orange maize enhances β-cryptoxanthin concentrations in egg yolks of laying hens better than tangerine peel fortificant. J Agric Food Chem. 2014 Dec 10;62(49):11892-900.

Huebner, S.M., J.M. Olson, J.P. Campbell, J.W. Bishop, P,M. Crump, and M.E. Cook. 2014. Dietary trans-10,cis-12 CLA reduces murine collagen-induced arthritis in a dose-dependent manner. J. Nutr. 144:177-184.

Whigham LD, Butz DE, Dashti H, Tonelli M, Johnson LK, Cook ME, Porter WP, Eghbalnia HR, Markley JL, Lindheim SR, Schoeller DA, Abbott DH, Assadi-Porter FM. 2014.Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. Curr Metabolomics. 2(4):269-278.

Whigham LD, Butz DE, Johnson LK, Schoeller DA, Abbott DH, Porter WP, Cook ME. 2013. Breath carbon stable isotope ratios identify changes in energy balance and substrate utilization in humans. Int J Obes (Lond). 2014 Jan 20.

Rehl JM, Shippy DC, Eakley NM, Brevik MD, Sand JM, Cook ME, Fadl AA. 2013.GidA expression in Salmonella is modulated under certain environmental conditions. Curr Microbiol. 2013 Sep;67(3):279-85. Epub 2013 Apr 12.

Cook ME. Fatty acids in immune health. In:Fats and Fatty Acids in Poultry Nutrition and Health, eds Cherian G, Poureslami R. Contect Products Ltd, Leicestershire, UK. 2012; Chapter 7, pp. 99-120.

Bobeck EA, Burgess KS, Jarmes TR, Piccione ML, Cook ME. 2012. Maternally-derived antibody to fibroblast growth factor-23 reduced dietary phosphate requirements in growing chicks. Biochem Biophys Res Commun. 420(3):666-70. Epub 2012 Mar 17.

Liu YQ, Davis CR, Schmaelzle ST, Rocheford T, Cook ME, Tanumihardjo SA 2012. .β-Cryptoxanthin biofortified maize (Zea mays) increases β-cryptoxanthin concentration and enhances the color of chicken egg yolk. Poult Sci. 91(2):432-8.

Krugner-Higby L., R. Brown, M. Rassette, M. Behr, O. Okwumabua, M. Cook, C. Bell, M.T. Flowers, J. Ntambi, A. Gendron. 2012. Ulcerative dermatitis in C57BL/6 mice lacking stearoyl CoA desaturase 1. Comp Med 62:257-263.

Cook, M.E. 2011. A review of science leading to host-targeted antibody strategies for preventing growth depression due to microbial colonization. J. Animal Sci. 89:1981-1990

Bobeck, E.A., K.M. Meyer, C. Helvig, M. Petkovick, and M.E. Cook. 2011. Sevelamer hydrochloride binds phosphate released from phytate in chicks fed 1a-hydroxycholecalciferol. J. Renal Nutr. 23:21-27.

Cook, ME and DL Trott. 2010. IgY-immune components of eggs as a source of passive immunity for animals and humans. World Poultry Sci. 66:215-225.

Huebner SM, Campbell JP, Butz DE, Fulmer TG, Gendron-Fitzpatrick A, Cook ME. 2010.Individual isomers of conjugated linoleic acid reduce inflammation associated with established collagen-induced arthritis in DBA/1 mice. J Nutr. 2010 Aug;140(8):1454-61. Epub 2010 Jun 23.

Leone VA, Worzalla SP, Cook ME. 2010. Evidence that maternal conjugated linoleic acid negatively affects lipid uptake in late-stage chick embryos resulting in increased embryonic mortality. Poult Sci. 89(4):621-32.

Pariza. MW, ME Cook. 2010. Determining the safety of enzymes used in animal feeds. Regulatory Toxixol and Pharma. 56:332-342

Aydin, R., ME Cook. 2009. Maternal dietary conjugated linoleic acid is not directly toxic for the developing chick embryo, but causes embryo mortality by altering fatty acid composition of the egg yolk in the chicken. J Sci Food Ag. 89:2687-2691.

Butz, DE, ME Cook, HR Egbalnia, F Assadi-Porter, WP Porter. 2009. Changes in the natural abundance of (CO2)-C-13/(CO2)-C-12 in breath due to lipopolysacchride-induced acute phase response. Rapid Comm. Mass Spec. 23:3729-3735

Fox, LM, DG Cox, JL Lockridge, X Wang, X Chen, L. Scharf, DL Trott, RM Ndonye, N. Veerapen, GS Bersra, AR Howell, ME. Cook, EJ Adams, WH Hildebrand JE Gumperz. 2009. Recognition of lyso-phospholipids by human natural killer T lymphocytes. PLOS Biology 7: Oct 7 (10) e1000228.

Leone, VA, DL Stransky, R. Aydin, ME Cook. 2009. Evidence for conjugated linoleic acid-induced embryonic morality that is independent of egg storage conditions and changes in egg relative fatty acids. Poultry Sci. 88: 1858-1868.

Leone, V. A., S. P. Worzalla, and M.E. Cook. 2009. Body compositional changes and growth alterations in chicks from hens fed conjugated linoleic acid. Lipids. 44:437-447.

Trott, D.L. M. Yang, J. Gonzales, A.E. Larson, W.H. Tepp, E.A. Johnson, and M.E. Cook. 2009 Egg yolk antibodies for detection and neutralization of Clostridium botulinum type A neurotoxin. J. Food Protection 72:1005-1011.

Aydin, R. and M.E. Cook 2008. The effects of dietary conjugated linoleic acid alone or in combination with linoleic acid and oleic acid on fatty acid composition of egg yolk, embryo mortality and chick yolk sac content retention in chickens. Animal Feed Sci Tech. 149:125-134.

Scanes, C.G., S.A. Cutler, R.W. Griffith, M.Yang, and M.E. Cook. 2008. Effects of egg antibody to components of inflammatory activation (phospholipase A2 and Toll like receptor 4) on the response of young turkeys to Salmonella typhimurium challenge. Avian Biology 1: 167-175.

Trott, D.L., M. Yang, P.L. Utterback, K.W. Koelkebeck, and M.E. Cook. 2008. Utility of spent Single Comb White Leghorn hens for production of polyclonal egg yolk antibody. J. Appl. Poultry Sci. 18:679-689.

Trott, D.L., E.M. Hellestad, M. Yang and M.E. Cook. 2008. Additions of killed whole bacteria cell preparations to Freund’s complete adjuvant alter laying hen antibody response to a soluble protein antigen. Poultry Sci. 87:912-917

Butz, D.E., G. Li, S. Huebner, and M.E. Cook 2007. A mechanistic approach to understanding conjugated linoelic acid’s role in inflammation using murine models of rheumatoid arthritis. Am J Physio Integr Comp Physiol 293: R669-R676.

Butz, D.E., G. Li, M.E. Cook 2006. t10,c12 conjugated linoleic acid induces compensatory growth after immune-challenge. J. Nutr Biochem. 17:735-741.

Li, G., D.E. Butz, and M.E. Cook. 2006. Selective conjugated fatty acids inhibit guinea pig platelet aggregation. Eu. J. Pharmacology 545:93-99.

Li, G., B. Dong, D.E. Butz, Y Park, M.W. Paiza, and M.E. Cook. 2006 NF-kB independent inhibition of lipopolysaccharide-induced cyclooxygenase by a conjugated linoleic acid cognate, conjugated nonadecadienoic acid. Biochem. Biophy. Acta. 1761(9):969-972

Li, G. D. Barnes, D. Butz, D. Bjorling, and M. E. Cook. 2005. 10t, 12c-conjugated linoleic acid inhibits lipopolysaccharide-induced cyclooxygenase protein expression in vitro and in vivo. J. Lipids Res. 46:2134-2142

Aydin, R., and M.E. Cook. 2005. Dietary conjugated linoleic acid to control the population of wild bird species considered pest. J. Wildlife Management. 70:1786-1788.

Aydin, R. and M. E. Cook. 2005. The effect of dietary conjugated linoleic acid on egg yolk fatty acids and hatchability in japanese quail. Poultry Sci. 83:2016-2022.

Aydin, R. and M. E. Cook 2005. The influence of conjugated linoleic acid enriched tallow on egg hatchability and quality in chickens. Internl. J Poultry Sci. 4 : 538-542

Clark, W.D., E.L. Smith, K.A. Kim, J.R. Paul-Murphy, P. Muir, and M. E. Cook. 2005. Osteocyte apoptosis and osteoclast-like cell appearance in chicken radii following osteotomy. Calcified Tissue Internl. 77:327-336.

Clark, W. D., E. L. Smith, K. A. Linn, J. R. Paul-Murphy, and M. E. Cook. 2005 . Use of peripheral quantitative computed tomography to monitor bone healing following radial osteotomy in  three-week-old chickens (Gallus domesticus). J. Avian Med. Surgery. 19:198-207.

Graves, E., A. Hitt, M.W. Pariza, M.E. Cook, and DE. O. McCarthy. 2005. Conjugated linoleic acid preserves gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. Res. Nurs. Health 28:48-55.

Park, Y., M. Yang, J.M. Storkson, K.J. Albright, W. Liu, M.E. Cook, and M.W. Pariza. 2005 Effects of CLA isomers on tumor necrosis factor-alpha secretion in mice. J. Food Biochem. 31:252-265

Cook, M.E. 2004. Antibodies: alternatives to antibiotics in improving growth and feed efficiency. J. Appl. Poultry Res. 13:106-119.

Cook, M. E., D. Butz, G. Li, M. W. Pariza, L. Whigham, and M. Yang. 2003. Conjugated linoleic acid enhances immune responses, but protects against the collateral damage of immune events. In: Advances in Conjugated Linoleic Acid Research, Volume 2, J. Sebedio, W. W. Christie, and R. Adlof, editors, AOCS Press, Champaign, IL, pp., 283-291.

Park Y, Storkson JM, Liu W, Albright KJ, Cook ME, Pariza MW. 2004. Structure-activity relationship of conjugated linoleic acid and its cognates in inhibiting heparin-releasable lipoprotein lipase and glycerol release from fully differentiated 3T3-L1 adipocytes. J Nutr Biochem. 2004 Sep;15(9):561-8.

Yang, M. and M. E. Cook. 2003. Dietary conjugated linoleic acid decreased cachexia, macrophage TNFa production and modifies splenocyte cytokines production. Exptl Biol. Med. 228:51-58.

Yang, M., and M. E. Cook. 2003. Dietary conjugated linoleic acid decreased weight loss and extended survival following the onset of kidney failure in NZB/W F1 mice. Lipids 38:21-24.

Attie, A. D., Y Hamon, A. R. Brooks-Wilson, M.P. Gray-Keller, M. L. E. MacDonald, V. Rigot, A. Tebon, L. Zhang, J. D. Mulligan, R. R. Singaraja, J. J. Bitgood, M. E. Cook, J. J. P Kastelein, G. Chimini, and M. R. Hayden. 2002. Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken. J Lipid Res. 43:1610-1617.

Cook,M. E. 2002. Regulation of eicosanoid pathways: A pathway to health and development. Pakistan J. Nutr. 1:103-105.

Whigham, L. D., A. Higbee, D. E. Bjorling, Y. Park, M.W. Pariza, and M. E. Cook. 2002. Conjugated linoleic acid reduces anti-induced prostaglandin and leukotriene release from sensitized guinea pig lung trachea, and bladder as measured by HPLC-tandem mass spectrometry. Am. J. Physiol. Regulatory. Integrative Comp. Physiol. 282:R1104-1112.

Aydin, R., M.W. Pariza, and M.E. Cook, 2001. Olive oil prevents the adverse effects of dietary conjugated linoleic acid on chick hatchability and egg quality. J. Nutr  131:800-806.

Dhurandhar, N.V, B.A. Israel, J.M. Kolesar, G. Mayhew, M.E. Cook, and R.L. Atkinson. 2001. Transmissibility of adenovirus-induced adiposity in a chicken model. Intnl. J. Obesity. 25:990-996.

Pariza, M.W., Y. Park, and M.E. Cook. 2001. The biologically active isomers of conjugated linoleic acid.  Progress Lipids Res. 40:283-298.

Stahl, J.L., E.B. Cook, M.A. Pariza, M.E. Cook, and F.M. Graziano, 2001. Effect of l-tryptophan supplementation on eosinophils and eotaxin in guinea pigs. Proc. Soc. Exptl. Biol. Med. 226: 177-184.

Turnock, L., M Cook, H. Steinberg, and C. Czuprynski, 2001. Dietary supplementation with conjugated linoleic acid does not alter resistance of mice to Listeria monocytogenes infection. Lipids  36:135-138.

Whigham, L.D., E.B. Cook, J.L. Stahl, R. Saban, D.E. Bjorling, M.W. Pariza and M.E. Cook, 2001.  Conjugated linoleic acid reduces antigen-induced histamine and prostaglandin E2 release from sensitized guinea pig trachea.  Am. J. Physiol. Regulatory. Integrative Comp. Physiol. 280: R908-R912

Cook, M.E., 2000. The interplay between modern management practices and the chicken: how immune response and the physiological mechanism for growth and feed efficiency have adapted over time. Where do we go from here. In: Biotechnology in the Animal Feed Industry (eds., T.P. Lyons and K.A. Jacques). Nottingham University Press, pp 97-110.

Cook, M.E., 2000.  Skeletal deformities and their causes.  Poultry Science 79:982-984.

Dhurandhar, N.V., B.A. Israel, J.M. Kolesar, G.F. Mayhew, M.E. Cook, and R.L. Atkinson, 2000. Increased adiposity in animals due to a human virus. Intl. J. Obesity 24:989-997

Pariza, M.W., Y. Park and M.E. Cook, 2000.  Mechanisms of action of conjugated linoleic acid.  Evidence and speculation.  Proc. Soc. Exptl. Biol. Med.  223: 8-13.

Park, Y., J. Storkson, J. Ntambi, M.E. Cook, C.J. Sih and M.W. Pariza, 2000 Inhibition of hepatic stearoyl-CoA desaturase activity by trans 10, cis 12 conjugated linoleic acid and its derivatives.  Biochim. Biophys. Acta. 1486:285-292.

Whigham, L.D., M.E. Cook, and R.L. Atkinson, 2000. Conjugated linoleic acid: implications for human health. Pharmacological Res. 42:503-510.

Yang, M., M.W. Pariza, M.E. and Cook, 2000.  Dietary linoleic acid protects against end stage disease of systemic lupus erythematosus in the NZB/W F1 mouse.  Immunopharma. Immunotox.  22:433-449.

Cook, M.E., 1999.  Nutritional Effects on Vaccination.   In:  Veterinary Vaccines and Diagnostics (ed. R. D. Schultz).  Advances in Veterinary Medicine  Vol. 41:  53-59.

Cook, M.E., D. DeVoney, B. Drake, M.W. Pariza, L. Whigham, and M. Yang, 1999.  Dietary control of immune-induced cachexia conjugated linoleic acid and immunity.  In:  Advances in Conjugated Linoleic Acid Research, Volume 1.  (editors  M.P. Yurawecz, M.M. Mossaba, J.K.G. Kramer, M.W. Pariza and G.J. Nelson) pp 226-237.

Park, Y., K. J. Albright, J. M. Storkson, W. Liu, M. E. Cook, and M. W. Pariza, 1999.  Changes in body composition in mice during  feeding and withdrawal of dietary conjugated linoleic acid. Lipids  34:  243-248.

Pariza, Michael W., Yeonwha Park and Mark E. Cook, 1999.  Conjugated Linoleic Acid and the Control of Cancer and Obesity.  Toxicological Sciences.  Toxicological Sciences.  52(Supplement):  107-110.

Cook, M.E. and M. Pariza, 1998.  The Role of Conjugated Linoleic Acid (CLA) in Health.  International Dairy J. 8:459-462.

Park, Y., K. J. Albright, W. Liu, J. M. Storkson, M. E. Cook and M. W. Pariza, 1997.  Effect of Conjugated Linoleic Acid on Body Composition in Mice.  Lipids.  32:853-858.

Wu, W., M.E. Cook, F.S. Chu, T. Buttles, J. Hunger, and P. Sutherland, 1997.  Case study of bovine dermatitis caused by oat straw infected with Fusarium sporotrichioides.  Vet. Rec.  140:399-400.

Chu, Q., W. Wu, M.E. Cook, and E.B. Smalley, 1996.  Elevated plasma glycosaminoglycans in chickens with tibial dyschondroplasia induced by a Fusarium oxysporum isolate.  Avian Dis. 40:715-719.

Cook, M.E., 1996.  Diet-induced immunosuppression.  Pages 317-328 in:   Poultry Immunology.  T.F. Davison, T.R. Morris, and L.N. Payne, ed.  Carfax Publishing Co., Oxfordshire, England.

Dafwang, I.I., M.L. Sunde, M.E. Cook, D.M. Schaefer, S.C. Ricke, D.J. Pringle, 1996.  Effect of antibiotics and water quality on the growth, intestinal characteristics and bacterial population of broiler chicks.  Nigerian Journal of Animal Production.  23(2):  116-23.

 Li, G., M.E. Cook, and W. Wu, 1996.  Reduction of ferricyanide by thiamine or thiamine pyrophosphate.  Biochem. Biophy. Res. Comm. 226:187-192.

Chu, Q., W. Wu, M.E. Cook, and E.B. Smalley, 1995.  Induction of tibial dyschondroplasia and suppression of cell‑mediated immunity in chickens by Fusarium oxysporum grown on sterile corn.  Avian Dis. 39:100-107.

Hatch, K.A., K.A. Sacksteder, I.W. Treichel, M.E. Cook, and W.P. Porter, 1995.  Early detection of catabolic state via change in 13C/12C ratio of blood protein.  Biochem. Biophys. Res. Comm. 212:719-726.

Wages, D.P., M.D. Ficken, M.E. Cook, and J. Mitchell, 1995.  Salt toxicosis in commercial turkeys.  Avian Dis. 39:158-161.

Bai, Y., and M.E. Cook, 1994.  Histological study of tibial dyschondroplasia from light-type chicks fed cysteine-supplemented diets.  Avian dis. 38:557-562.

Bai, Y., M.L. Sunde, and M.E. Cook, 1994.  Egg production of laying hens before and after force-molting is not correlated.  Appl. Poultry Res. 3:127-132.

Bai, Y. M.L. Sunde, and M.E. Cook, 1994.  Molybdenum but not copper counteracts cysteine-induced tibial dyschondroplasia in broiler chicks.  J. Nutr. 124:588-593.

Chin, S.F., J.M. Storkson, K.J. Albright, M.E. Cook, and M.W. Pariza, 1994.  Conjugated linoleic acid is a growth factor for rats as shown by enhanced weight gain and improved feed efficiency.  J. Nutr. 124:2344-2349.

Cook, M.E., Y. Bai, and M. Orth, 1994.  Factors influencing growth plate cartilage turnover.  Poultry Sci. 73:889-896.

Miller, C.C., and M.E. Cook, 1994.  Evidence against the induction of immunological tolerance by feeding antigens to chickens.  Poultry Sci. 73:106-112.

Miller, C.C., Y. Park, M.W. Pariza, and M.E. Cook, 1994.  Feeding conjugated linoleic acid to animals partially overcomes catabolic responses due to endotoxin injection.  Biochem. Biophys. Res. Comm. 198:1107‑1112.

Orth, M.W., and M.E. Cook, 1994.  Avian tibial dyschondroplasia: a description of the growth plate disease as well as the conditions that induce it.  Vet. Pathol. 31:403-414.

Orth, M.W., R.M. Leach, A.C. Vailas, and M.E. Cook, 1994.  Non‑reducible collagen cross‑linking in cartilage from broiler chickens with tibial dyschondroplasia.  Avian Dis. 38:44‑49.

Banik, M.T., J.A. Paul, H.H. Burdsall, and M.E. Cook, 1993.  Serological differentiation of two forms of Phellinus weirii.  Mycologia 85:605-611.

Cook, M.E., C.C. Miller, Y. Park, and M. Pariza, 1993.  Immune modulation by altered nutrient metabolism.  Nutritional control of immune-induced growth depression.  Poultry Sci. 72:1301-1305.

Orth, M.W., D.A. Martinez, M.E. Cook, and A.C. Vailas, 1993.  The presence of lysylpyridinoline in the hypertrophic cartilage of newly hatched chicks.  Biochimica Biophys. Acta 1157:229‑232.

Wu, W., M.E. Cook, Q. Chu, and E.B. Smalley, 1993.  Tibial dyschondroplasia of chickens induced by fusarochromanone, a mycotoxin.  Avian Dis. 37:302‑309.

Bai, Y., M.L. Sunde, and M.E. Cook, 1992.  Wheat middlings as an alternate feedstuff for laying hens.  Poultry Sci. 71:1007-1014.

Orth, M.W., Y. Bai, I.H. Zeytun, and M.E. Cook, 1992.  Excess levels of cysteine and homocysteine induce tibial dyschondroplasia (TD) in broiler chicks.  J. Nutr. 122:482-487.

Pimentel, J.L., M.E. Cook, and J.L. Greger, 1992.  Anemia induced by ingestion of excess zinc in chicks: Importance of red blood cell turnover.  J. Nutr. Biochem. 3:146-150.

Pimentel, J.L., J.L. Greger, M.E. Cook, and J.L. Stahl, 1992.  Iron metabolism in chicks fed various levels of zinc and copper.  J. Nutr. Biochem. 3:140-145.

Cook, M.E., 1991.  Nutrition and the immune response of the domestic fowl.  CRC Poultry Biology 3:167-189.

Cook, M.E., 1991.  Mycotoxin and nutrient interactions.  40th Western Dis. Conf., pp. 51-54.

Orth, M.W., D.A. Martinez, M.E. Cook, and A.C. Vailas, 1991.  Non-reducible crosslink formation in tibial dyschondroplastic growth plate cartilage from broiler chicks fed homocysteine.  Biochem. Biophys. Res. Comm. 179:1582-1586.

Payne, C., M.E. Cook, T.M. Ellis, and R.E. Hams, 1991.  ELISA testing of U.S. breeders and layers for big liver and spleen disease (BLS).  40th Western Dis. Conf., pp. 216-218.

Pimentel, J.L., M.E. Cook, and J.L. Greger, 1991.  Bioavailability of zinc-methionine for chicks.  Poultry Sci. 70:1637-1639.

Pimentel, J.L., M.E. Cook, and J.L. Greger, 1991.  Immune response of chicks fed various levels of zinc.  Poultry Sci. 70:947-954.

Pimentel, J.L., M.E. Cook, and J.M. Jonsson, 1991.  Research Note: Increased growth of chicks and poults obtained from hens injected with jackbean urease.  Poultry Sci. 70:1842-1844.

Poernama, F., R. Subramanian, M. Cook, and A. Attie, 1991.  High density lipoprotein deficiency syndrome in chickens is not associated with an increased susceptibility to atherosclerosis.  Arteriosclerosis thrombosis 12:601-607.

Wu, W., M.E. Cook, and E.B. Smalley, 1991.  Decreased immune response and increased incidence of tibial dyschondroplasia caused by Fusaria grown on sterile corn.  Poultry Sci. 70:293‑301.

Burdsall, H.H., M. Banik, and M.E. Cook, 1990.  Serological differentiation of three species of Armillaria and Lentinula edodes by enzyme-linked immunosorbent assay using immunized chickens as a source of antibodies.  Mycologia 82:415-423.

Poernama, F., S.A. Schreyer, J.J. Bitgood, M.E. Cook, and A.D. Attie, 1990.  Spontaneous high density lipoprotein deficiency syndrome associated with a Z-linked mutation in chickens.  J. Lipid Res. 31:955-963.

Schrank, C.S., M.E. Cook, and W.R. Hansen, 1990.  Immune response of mallard ducks treated with immunosuppressive agents: Antibody response to erythrocytes and in vivo response to phytohemagglutinin-P.  J. Wildlife Dis. 26:307-315.

Stahl, J.L., J.L. Greger, and M.E. Cook, 1990.  Breeding-hen and progeny performance when hens are fed excessive dietary zinc.  Poultry Sci. 69:259-263.

Wu, W., M.E. Cook, and E.B. Smalley, 1990.  Prevention of thiram-induced dyschondroplasia by copper.  Nutr. Res. 10:555-557.

Wu, W., P.E. Nelson, M.E. Cook, and E.B. Smalley, 1990.  Fusarochromanone production by Fusarium isolates.  Appl. Envir. Micro. 56:2989‑2993.

Stahl, J.L., M.E. Cook, and J.L. Greger, 1989.  Zinc, iron and copper content of eggs from hens fed varying levels of zinc.  J. Food Composition 1:309-315.

Stahl, J.L., M.E. Cook, M.L. Sunde, and J.L. Greger, 1989.  Enhanced humoral immunity in progeny chicks from hens fed practical diets supplemented with zinc.  Appl. Agric. Res. 4:86-89.

Stahl, J.L., J.L. Greger, and M.E. Cook, 1989.  Zinc, copper, and iron utilisation by chicks fed various concentrations of zinc.  Brit. Poultry Sci. 30:123-134.

Chu, Q., M.E. Cook, W. Wu, and E.B. Smalley, 1988.  Research Note:  Immune and bone properties of chicks consuming corn contaminated with a Fusarium that induces dyschondroplasia.  Avian Dis. 32:132‑136.

Pimentel, J.L., and M.E. Cook, 1988.  Improved growth in the progeny of hens immunized with jackbean urease.  Poultry Sci. 67:434-439.

Ricke, S.C., D.M. Schaefer, M.E. Cook, and K.H. Kang, 1988.  Differentiation of ruminal bacterial species by enzyme-linked immunosorbent assay using egg yolk antibodies from immunized chicken hens.  Appl. Envir. Micro. 54:596-599.

Tsiagbe, V.K., M.E. Cook, A.E. Harper, and M.L. Sunde, 1988.  Alterations in phospholipid composition of egg yolks from laying hens fed choline- and methionine-supplemented diets.  Poultry Sci. 67:1717-1724.

Bates, D.P., L.E. Hanson, M.E. Cook, B.C. Wentworth, M.L. Sunde, and J.J. Bitgood, 1987.  Lighting and sex ratio for breeding ringnecked pheasants in confined housing.  Poultry Sci. 66:605-612.

Dafwang, I.I., M.E. Cook, and M.L. Sunde, 1987.  Interaction of dietary antibiotic supplementation and stocking density on broiler chick performance and immune response.  Brit. Poultry Sci. 28:47-55.

Gildersleeve, R.P., D.G. Satterlee, T.R. Scott, D.I. McRee, C.R. Parkhurst, M.E. Cook, 1987.  Hematology of Japanese quail selected for high or low serum corticosterone responses to complex stressor.  Comp. Biochem. Physiology: Physiology A 86A:569-573.

Greger, J.L., M.L. Storey, J.L. Stahl, M.E. Cook, S.E. Gentry-Roberts, and J.C. Lynds, 1987.  Zinc, iron and copper interactions in humans, rats and chicks.  Tr. Elem. Nutr. in Man and Animals 6:231-232.

Pimentel, J.L., and M.E. Cook, 1987.  Suppressed humoral immunity in chicks fed diets deficient in sodium, chloride, or both sodium and chloride.  Poultry Sci. 66:2005-2010.

Tsiagbe, V.K., M.E. Cook, A.E. Harper, and M.L. Sunde, 1987.  Assessment of softness properties of feathers.  Poultry Sci. 66:1600-1602.

Tsiagbe, V.K., M.E. Cook, A.E. Harper, and M.L. Sunde, 1987.  Efficacy of cysteine in replacing methionine in the immune responses of broiler chicks.  Poultry Sci. 66:1138-1146.

Tsiagbe, V.K., M.E. Cook, A.E. Harper, and M.L. Sunde, 1987.  Enhanced immune responses in broiler chicks fed methionine-supplemented diets.  Poultry Sci. 66:1147-1154.

Tsiagbe, V.K., R.J. Straub, M.E. Cook, A.E. Harper, and M.L. Sunde, 1987.  Critical vitamin supplementation of broiler diets high in alfalfa juice protein.  Poultry Sci. 66:1771-1778.

Tsiagbe, V.K., R.J. Straub, M.E. Cook, A.E. Harper, and M.L. Sunde, 1987.  Formulating wet alfalfa juice protein concentrate diets for chicks.  Poultry Sci. 66:1023-1027.

Ameenuddin, S., M.L. Sunde, H.F. DeLuca, and M.E. Cook, 1986.  Excessive cholecalciferol in a layers diet: Decline in some aspects of reproductive performance and increased bone mineralisation of progeny.  Brit. Poultry Sci. 27:671-677.

Crenshaw, T.D., M.E. Cook, J. Odle, and R.E. Martin, 1986.  Effect of nutritional status, age at weaning, and room temperature on growth and systemic immune response of weanling pigs.  J. Anim. Sci. 63:1845-1853.

Dafwang, I.I., M.E. Cook, D.J. Pringle, and M.L. Sunde, 1986.  Nutritional value of aerobically fermented poultry manure and offal (Fermway) for broiler chicks.  Poultry Sci. 65:1765-1770.

Patterson, P.H., M.E. Cook, T.D. Crenshaw, and M.L. Sunde, 1986.  Mechanical properties of the tibiotarsus of broilers and poults loaded with artificial weight and fed various dietary protein levels.  Poultry Sci. 65:1357-1364.

Stahl, J.L., M.E. Cook, and M.L. Sunde, 1986.  Zinc supplementation: Its effect on egg production, feed conversion, fertility, and hatchability.  Poultry Sci. 65:2104-2109.

Dafwang, I.I., M.E. Cook, M.L. Sunde, and H.R. Bird, 1985.  Bursal, intestinal, and spleen weights and antibody response of chicks fed subtherapeutic levels of dietary antibiotics.  Poultry Sci. 64:634-639.

Cook, M.E., P.H. Patterson, and M.L. Sunde, 1984.  Leg deformities: Inability to increase severity by increasing body weight of chicks and poults.  Poultry Sci. 63:620-627.

Cook, M.E., W.T. Springer, and J.A. Hebert, 1984.  Enhanced incidence of leg abnormalities in reovirus WVU 2937 infected chickens fed various dietary levels of selected vitamins.  Avian Dis. 28:548-561.

Cook, M.E., W.T. Springer, K.M. Kerr, and J.A. Hebert, 1984.  Severity of tenosynovitis in reovirus-infected chickens fed various dietary levels of choline, folic acid, manganese, biotin, or niacin.  Avian Dis. 28:526-573.

Cook, M.E., M.L. Sunde, J.L. Stahl, and L.E. Hanson, 1984.  Zinc deficiency in pheasant chicks fed practical diets.  Avian Dis. 28(4):1102-1109.

Cook, M.E., and W.T. Springer, 1983.  Effect of reovirus infection and dietary levels of selected vitamins on immunocompetence of chickens.  Avian Dis. 27:367-377.

Cook, M.E., and M.L. Sunde, 1983.  Performance of chicks fed diets composed of single ingredients or combinations of ingredients: A laboratory demonstration for undergraduates.  World’s Poultry Sci. J. 40:207-214.

Cook, M.E., T.R. Scott, J.A. Hebert, and W.A. Johnson, 1982.  Effects of blood sampling by cardiac puncture on subsequent body weights of boilers.  Poultry Sci. 61:2506-2508.

Cook, M.E., and M.W. Pariza, 1995.  Method for increasing the efficiency of feed conversion in animals
US Patent 5,428,072.

Cook, M.E., and M.W. Pariza, 1995.  Methods for preventing weight loss, reduction in weight gain, and anorexia due to immune stimulation.  US Patent 5,430,066.

Cook, M.E., M.W. Pariza, K.N. Lee, and B.C. Wentworth, 1996.  Method for controlling bird populations
US Patent 5,504,114.

Cook, M.E., M.W. Pariza, and Y. Park, 1996.  Method for reducing body fat in animals. 
US Patent: 5,554,646.

Cook, M.E., E.B. Cook, J.L. Stahl, F.M. Graziano, and M.W. Pariza, 1996.  Methods of attenuating the allergic response in animals.  US Patent 5,585,400.

Cook, M.E., M.W. Pariza, X. Yang, and D. Devoney, 1997.  Methods of treating animals to maintain or increase CD-4 and CD-8 cell populations.  US Patent 5,674,901.

Cook, M.E., and D.L. Jerome, 1998.  Method of improving the growth or the efficiency of feed conversion of an animal and compositions for use therein.  US Patent 5,725,873.

Cook, M.E., M.W. Pariza, 1998.  Dietetic foods containing conjugated linoleic acid. 
US Patent  5,760,082.

Cook, M.E., M.W. Pariza, and D.L. Jerome, 1998.  Method for preventing skeletal problems in poultry
US Patent 5,760,083.

Cook, M.E., and M.W. Pariza, 1998.  Methods of treating animals to maintain or enhance bone mineral content and compositions for use therein. 
US Patent 5,804,210.

Cook, M.E., C.C. Miller, and J.L. Pimentel, 1998.  Novel compound to mimic a naturally occurring peptide effect.  U.S. Patent 5,814,316.

Cook, M.E., and M.W. Pariza, 1998.  Method for maintaining an existing level of body fat and/or body weight. 
US Patent 5,814,663.

Cook, M.E., C.C. Miller, and J.L. Pimentel, 1998.  CCK antibodies used to improve feed efficiency.
US Patent  5,827,517.

Cook, M.E. and M.W. Pariza, 1998.  Method of treating  animals to maintain or increase CD-4 and CD-8 cell population.  US Patent 5,827,885.

Cook, M.E., D.L. Jerome, M.W. Pariza, and D. Buege, 1998.  Method for increasing fat firmness and improving meat quality in animals.  Pending.  US Patent 5,851,572.

Cook, M.E., Y. Park, and M.W. Pariza, 1999.  Method for controlling body fat and/or body weight in animals and pharmaceutical compositions for use therein.  US Patent 5,855,917.

Koegel, R.G., R.J. Straub, S. Austin-Phillips, and M.E. Cook, 1999.  Animal feed compositions containing phytase derived from transgenic alfalfa and methods of use thereof.  U.S. Patent  5,900,525.

Porter, W.P., I.W. Treichel, and M.E. Cook, 1999.  Passive measurement of isotopes to monitor health.   US Patent 5,912,178.

Cook, M.E., S. Kim, M.W. Pariza, D. DeVoney, 1999.  Method of treating animals to enhance natural killer lymphocyte function.  US Patent 5,914,346.

Cook, M.E. and D.L. Jerome, 1999.  Method of improving the growth or the efficiency of feed conversion of an animal and compositions for use therein.  U.S. Patent  5,919,451.

Cook, M.E., Cheryl C. Miller and Julio L. Pimentel, 1999.  CCK antibodies used to improve feed efficiency
U.S. Patent 5,989,584.

Cook, M.E., D. Jerome, and M.W. Pariza, 2000.  Method for selectively altering body fat levels, feed efficiency, or weight gain.  U.S. Patent  6,020,378.

Cook, M.E., L.D. Whigham, and M.W. Pariza, 2000. Selective inhibition of cyclooxygenase-2.
U.S. Patent 6,077,868.

Cook, M.E. and M.W. Pariza, 2000. Methods of treating animals to maintain or increase CD-4 and CD-8 cell populations. U.S. Patent 6,020376.

Cook, M.E., D.L. Jerome, M.W. Pariza, D.R. Buege, P. Mozdziak, 2000. Method of increasing fat firmness and improving meat quality in animals. U.S. Patent 6,060,087.

Cook, M.E., R. Aydin, and M.W. Pariza, 2000. Eggs enriched with conjugated linoleic acid and method of making same. U.S. Patent  6,113,973.

Cook, M. E. 2001. Method of using anti-phospholipase A2 antibodies to enhance growth or improve feed efficiency. U. S. Patent 6,213,930 B1.

Cook, M. E. 2002. Method of using anti-phospholipase A2 antibodies to enhance growth or improve feed efficiency. US Patent 6,383,485.

Cook, M. E. , M. Yang, and M. W. Pariza. 2002. Method of increasing life longevity and preventing body weight wasting in autoimmune disease by using conjugated linoleic acid. US Patent 6,395,782.

Cook, M.E., B. M. Drake, L.S. Girsh, J. R. Jackson. 2003. A method to prevent the formation and enhance the breakdown of bezoars in animals and humans. US Patent 6,562,366 B2.

Rutledge, J.J. R.L. Monson, C.C. Cook, M.E. Cook. 2006. Composition containing gamete or embryo and animal white yolk and the use thereof. US Patent 7,083,909

Assadi-Porter, FM, ME Cook, WP Porter, DE Butz 2008. Identification of disease characteristic using isotope ratios in breath. US Patent 7,465,276

Cook, ME, M Yang, K Roberson. 2009 Method for improving body weight uniformity and increasing carcass yield in animals. US Patent 7,579,002

Cook, M.E., M. Yang, and M. Etzel. 2010. Methods for heat-stabilizing proteins with specific binding activities.
US Patent 7,750,117.

Attie, AD, M. Gray-Keller, M Cook, M.R. Hayden, S. Pimstone, A. Brooks-Wilson. 2007. Cholesterol transport gene. U.S. Patent 7,166,584.

Assadi-Porter, FM, ME. Cook, HR Eghbalnia, M. Tonelli, WP Porter, DE Butz. 2009 (April 23). Noninvasive measurement and identification of biomarkers in disease state. US Patent Appl. 20090104596 A1.

Cook ,M.E., D.L. Trott, M. Yang. 2009 (April 9). Immunogenic composition. US Patent appl. 2009/00926.39 A1.

Cook, M.E., M. Petkovich, C. Helvig, E. Hellestad, K. Crawford. 2010. Methods of reducing phosphate absorption. US Appl. 2010/0166760 A1

Cook, Mark, Martin Petkovich, Erica Hellestad. 2010. Methods for reducing phosphate absorption. Application. US2010/0143385 A1

Cook, Mark E., David L. Trott, Daniel Butz. 2010. Eggs having increased antibody titer and methods for making same. Application. US 2007/0231320 A1.

Assadi-Porter, F.M., M.E. Cook, H.R. Eghbalnia, M. Tonelli, W.P. Porter, D.E. Butz. 2011. Noninvasive measurement and identification of biomarkers in disease state. U.S. Patent 8026049.

Cook, M.E., M. Yang, D.M. Barnes. 2011. Method for enhancing growth or increasing feed efficiency through reducing binding between endotoxin and its receptor in the gastrointestinal tract. US 7,883,701.

Cook, M. and D. Trott. 2011 Use of corticosterone for increasing egg antibody. US 2011/0003382 A1

Eghbalnia, H.E., M.E. Cook, W.P. Porter, and D.E. Butz. 2013. Detection of rate changes in systemic oscillations of metabolic pathways by monitoring isotope ratios. U.S. Patent 8,512,676.

Assadi-Porter, F.M., Cook, M.E., Porter, W.P., and Butz, D.E.2013. Identification of disease characteristics using isotope ratios in breath. U. S. Patent 8,435,187

Sand, J.M., and M.E. Cook. 2014. Interleukin-10 peptides and antibodies thereof for inhibiting adverse effects of protozoan infection. U.S. Patent 8,652,457

Cook, M.E., M. Petkovich, C. Helvig, E. Hellestad, and K. Crawford. 2014. Method of reducing phosphate absorption by administering orally an IgY anti-intestinal sodium phosphate cotransporter type 2B antibody.
U.S. Patent 8,802,094.

Assadi-Porter, F.M., M.E. Cook, W.P. Porter, and D.E. Butz. 2014. Identification of disease characteristics using isotope ratios in breath. US Patent 8,852,117.

Cook, M. M. Petkovich, C. Helvig, E. Hellestad, K. Crawford, 2014. Method for reducing phosphate absorption. U.S. Patent 8,877,198

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